Weight Loss Improves Beta Cell Function in Type 2 Diabetes

For the first time, these changes have been shown to correlate with a decrease in pancreatic polypeptide, reported Hana Kahleova, MD, from the diabetes centre at the Institute for Clinical and Experimental Medicine in Prague, Czech Republic. Amplify’d from http://www.medscape.com Weight Loss Improves Beta Cell Function in Type 2 Diabetes December 7, 2011 (Dubai, United …

Can Gastric Bypass “Cure” Diabetes? Can it Go Too Far?

Can Gastric Bypass "Cure" Diabetes? Can it Go Too Far? Gastric bypass (GB) surgery is associated with postprandial hyperinsulinemia, and this effect is accentuated in postsurgical patients who develop recurrent hypoglycemia. Plasma levels of the incretin glucagon-like peptide 1 (GLP-1) are dramatically increased after GB, suggesting that its action contributes to alteration in postprandial glucose …

Orlistat Improves Diabetes

Orlistat improved lipid profile and led to faster glycaemic control and insulin resistance parameters than the control, without any serious adverse event.Amplify’d from http://www.ncbi.nlm.nih.govJ Clin Pharm Ther. 2011 Aug 4. doi: 10.1111/j.1365-2710.2011.01280.x. [Epub ahead of print]Effects of 1-year orlistat treatment compared to placebo on insulin resistance parameters in patients with type 2 diabetes.Derosa G, Cicero …

Special Conjugated linoleic acid (CLA) **Isomers** Lead to Lowering Body Fat

Special Conjugated linoleic acid (CLA) **Isomers** Lead to Lowering Body Fat CLA caused a clear reduction in **fat** mass (retroperitoneal and mesenteric), aand no other tissues were affected. Conjugated linoleic acid (CLA) modulates body composition, especially by reducing adipose tissue. However, despite the increasing knowledge about CLA's beneficial effects on obesity management, the mechanism of …

Gastric Band <1/2 as Good as Gastric Bypass

Gastric Band <1/2 as Good as Gastric Bypass LAGB patients lost significantly less weight than the LRYGB patients (24.6% compared to 44.0% Excess Wt Lost LAGB reduced HOMA from 3.6 to 2.3 and LRYGB reduced HOMA from 4.4 to 1.4Amplify’d from http://www.ncbi.nlm.nih.govObes Surg. 2009 Sep;19(9):1297-303. Epub 2009 Jul 23.The surgical treatment of type II diabetes …

Glucagon-like peptide-1

You should know that Glucagon-like peptide-1 *increases insulin secretion *increases insulin-sensitivity *increases beta cells **decreases food intake by increasing satiety.** Gastric Bypass => Increases GLP1Amplify’d from en.wikipedia.orgGlucagon-like peptide-1Glucagon-like peptide-1 (GLP-1) is derived from the transcription product of the proglucagon gene. The major source of GLP-1 in the body is the intestinal L cell that secretes …